4.4 Article

Organocatalytic α-oxybenzoylation of aldehydes

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TETRAHEDRON LETTERS
卷 50, 期 26, 页码 3625-3627

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PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.03.082

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  1. Engineering and Physical Sciences Research Council [GR/T04113/01] Funding Source: researchfish

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A simple method for the asymmetric alpha-oxybenzoylation of aldehydes is presented. Treatment of a series of aldehydes with benzoyl peroxide in the presence of a MacMillan imidazolidinone leads directly to the alpha-oxybenzoylated product with excellent levels of asymmetric induction. (C) 2009 Elsevier Ltd. All rights reserved.

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