期刊
TETRAHEDRON LETTERS
卷 50, 期 1, 页码 15-18出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2008.09.159
关键词
Copper-mediated; N-Arylation; O-Arylation; Arylboronic acid; Continuous flow; Microreactor; Scalability
资金
- University of Leuven
- FWO (Fund for Scientific Research-Flanders (Belgium))
A continuous flow procedure has been elaborated for the copper(II)-mediated N- and O-arylation of a range of compounds with arylboronic acids using a commercial microreactor setup. The compounds could be continuously generated in good yields paving the way for efficient scalability. (C) 2008 Published by Elsevier Ltd.
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