期刊
TETRAHEDRON LETTERS
卷 50, 期 17, 页码 1943-1946出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.02.049
关键词
-
资金
- Spanish Ministry of Science and Education [AYA2006-15648-C02-01]
- Grant Agency of Czech Republic [203/09/11193]
- Ministry of Education of Czech Republic
A highly enantioselective organocatalytic synthesis of piperidines is reported. The reaction is catalyzed by simple and commercially available secondary amines, affording the corresponding adducts with high yields and enantioselectivities. Moreover, this reaction is used for the formal synthesis of (-)-Paroxetine, a blockbuster drug, in only three steps. (C) 2009 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据