期刊
TETRAHEDRON LETTERS
卷 50, 期 26, 页码 3299-3301出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.02.073
关键词
Sonogashira cross-coupling; Alkynes; Annulation; Furopyridinones; Microwave-assisted synthesis
资金
- Bayer CropScience
- CNRS
- French Ministry of Higher Education and Research (MESR)
N-Alkyl-3-aryl-5-iodo-4-methoxypyridin-2(1H)-ones readily undergo sequential acetylide cross-coupling, demethylation, and furan annulation under classical Sonogashira reaction conditions to furnish 7-arylfuro[3,2-c]pyridin-4(5H)-ones, a class of hitherto unknown compounds, in a one-pot operation. Microwave irradiation was found to significantly reduce reaction times and to allow lower catalysts and reagent loadings. (C) 2009 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据