期刊
TETRAHEDRON LETTERS
卷 49, 期 36, 页码 5309-5311出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2008.06.080
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资金
- Science and Engineering Research Council of A*STAR (Agency for Science, Technology and Research), Singapore
- Johnson & Johnson Asia Pacific
The synthesis of 3-, 4-, 7-bromo and 4,7-dibrominated 5,6-dihydroxyindole (DHI) and 5,6-dihydroxyindole-2-carboxylic acid (DHICA) derivatives is reported. Hemetsberger and Bartoli indole syntheses were investigated and expedient routes to the desired compounds were developed. These indoles are valuable substrates for elaboration using transition metal-mediated cross-coupling chemistry. (C) 2008 Elsevier Ltd. All rights reserved.
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