期刊
TETRAHEDRON
卷 70, 期 31, 页码 4645-4651出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2014.05.045
关键词
Domino reaction; sp(3) C-H functionalization; alpha-Ketothioamides
资金
- National Natural Science Foundation of China [21032001, 21272085]
A domino reaction that involves the formation of C=S and C-N bonds in one process via sp(3) C-H functionalization strategy has been developed. This reaction affords an efficient and direct method for the synthesis of alpha-ketothioamides from aryl methyl ketones, amines, and sodium hydrosulfide under the promotion of iodine. (C) 2014 Elsevier Ltd. All rights reserved.
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