4.4 Article

Facile, efficient synthesis of polyfunctionalized 2-aminoimidazoles via vinyl azides and cyanamide

期刊

TETRAHEDRON
卷 70, 期 7, 页码 1418-1421

出版社

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2014.01.007

关键词

2-Aminoimidazoles; Vinyl azides; Cyanamide; Direct synthesis

资金

  1. National Natural Science Foundation of China [81273356]
  2. Natural Science Foundation of Zhejiang Province [Z2110655]
  3. Doctoral Program of Higher Education [20100101110105]
  4. Zhejiang Leading Team of ST Innovation
  5. Diabetes National Research Group, USA.

向作者/读者索取更多资源

A simple and direct synthesis of 2-aminoimidazoles from vinyl azides and cyanamide was developed. An attractive feature of this protocol is that the desired products are generated in a highly efficient and eco-friendly manner without the use of a catalyst. A plausible mechanism has been proposed. (C) 2014 Elsevier Ltd. All rights reserved.

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