期刊
TETRAHEDRON
卷 70, 期 7, 页码 1418-1421出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2014.01.007
关键词
2-Aminoimidazoles; Vinyl azides; Cyanamide; Direct synthesis
资金
- National Natural Science Foundation of China [81273356]
- Natural Science Foundation of Zhejiang Province [Z2110655]
- Doctoral Program of Higher Education [20100101110105]
- Zhejiang Leading Team of ST Innovation
- Diabetes National Research Group, USA.
A simple and direct synthesis of 2-aminoimidazoles from vinyl azides and cyanamide was developed. An attractive feature of this protocol is that the desired products are generated in a highly efficient and eco-friendly manner without the use of a catalyst. A plausible mechanism has been proposed. (C) 2014 Elsevier Ltd. All rights reserved.
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