期刊
TETRAHEDRON
卷 69, 期 44, 页码 9277-9283出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2013.08.045
关键词
Benzopyranone; Copper; Subcritical water; Microwave; Urolithins
资金
- Thailand Research Fund [RMU5380021]
- Centre of Excellence on Environmental Health and Toxicology (EHT)
- Science & Technology Postgraduate Education and Research Development Office (PERDO)
- Ministry of Education
Benzopyranones were successfully synthesized using Cu(I)-mediated C-O bond formation in subcritical water. A number of benzopyranone derivatives including polymethoxy benzopyranones, benzopyranopyridones, cbromenoindolones, and furochromenones were synthesized in satisfactory yield. This methodology was further applied to synthesize the intestinal microbial metabolites, urolithins A, B, and C, which were found to exhibit potent antioxidant activity. (C) 2013 Elsevier Ltd. All rights reserved.
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