期刊
TETRAHEDRON
卷 69, 期 34, 页码 7011-7018出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2013.06.049
关键词
Pyrroles; Multicomponent reaction; One-pot synthesis; Gluconic acid aqueous solution; Green solvent
资金
- National Natural Science Foundation of China [21272053, 21072042, 20872025]
- Nature Science Foundation of Hebei Province [B2011205031]
Four-component coupling of amines, aldehydes, 1,3-dicarbonyl compounds, and nitromethane has been achieved in gluconic acid aqueous solution (GAAS) to produce polysubstituted pyrroles in high yield. Gluconic acid aqueous solution could be recycled and reused several times without significant loss of its efficiency. (C) 2013 Elsevier Ltd. All rights reserved.
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