4.4 Article

Copper-catalyzed synthesis of α,β-unsaturated acylamides via direct amidation from cinnamic acids and N-substituted formamides

期刊

TETRAHEDRON
卷 69, 期 35, 页码 7258-7263

出版社

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2013.06.078

关键词

Amidation; Cinnamamide; N-Substituted formamide; Ligand-free; Cinnamic acid

资金

  1. International S&T Cooperation Program of Jiangsu Province [BZ2010048]
  2. Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry
  3. Priority Academic Program Development of Jiangsu Higher Education Institutions
  4. Key Laboratory of Organic Synthesis of Jiangsu Province

向作者/读者索取更多资源

A highly effective synthesis of alpha,beta-unsaturated acylamides is reported for the first time via copper-catalyzed direct amidation between readily available cinnamic acids and N-substituted formamides. The protocol was easily accessible and practical. (C) 2013 Elsevier Ltd. All rights reserved.

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