期刊
TETRAHEDRON
卷 69, 期 9, 页码 2113-2117出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2013.01.021
关键词
Gorgonian-derived fungus; Aspergillus sp.; Cyclic tetrapeptide; Asteltoxin; Antifouling
资金
- 973 Program of China [2010CB833803]
- 863 Program of China [2012AA092104]
- National Natural Science Foundation of China [40931160435, 40976090]
- Knowledge Innovation Program of CAS [KSCX2-EW-G-12B]
Three new cyclic tetrapeptides, aspergillipeptides A-C (1-3), and one new asteltoxin B (4) were isolated from a culture broth of gorgonian-derived fungal strain Aspergillus sp. SCSGAF 0076. Their structures were elucidated by spectroscopic analysis, and the absolute configurations of aspergillipeptides A-C were determined by Marfey's method. Aspergillide C (3) showed strong antifouling activity against Bugula neritina larvae settlement with LC50/EC50>25. (c) 2013 Elsevier Ltd. All rights reserved.
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