A new synthetic approach for functional triisopropoxyorganosilanes using molecular building blocks

We report an efficient synthetic approach for well-designed organic-bridged alkoxysilanes, which allow the formation of highly functional organosilica hybrids under mild sol gel conditions. A series of molecular building blocks containing a triisopropoxysilyl group were synthesized and used in cross-coupling reactions. The triisopropoxysilyl group showed a good tolerance for various organic transformations. 1,4-Diketo-3,6-dithienylpyrrolo[3,4-c]pyrrole-bridged triisopropoxysilane was successfully prepared, allowing rapid formation of organosilica hybrid without loss of functionality under mildly acidic conditions. (C) 2013 Elsevier Ltd. All rights reserved.