期刊
TETRAHEDRON
卷 69, 期 1, 页码 212-218出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2012.10.042
关键词
Trityl chloride; Multi-component condensation; 1-Amido-alkyl-2-naphthol; 1-Thioamido-alkyl-2-naphthol; 1-Carbamato-alkyl-2-naphthol; Solvent-free
资金
- Research Affairs Office of Bu-Ali Sina University [32-1716]
- Payame Noor University
- Center of Excellence in Development of Chemical Method (CEDCM), Hamedan, I.R. Iran
Trityl chloride (TrCl), efficiently catalyzes the one-pot multi-component condensation of beta-naphthol with aromatic aldehydes and amides/thioamides/carbamates such as acetamide, benzamide, nicotinamide, thioacetamide, and methylcarbamate under solvent-free and neutral conditions to afford 1-amido-alkyl-2-naphthols, 1-thioamido-alkyl-2-naphthols, and 1-carbamato-alkyl-2-naphthols in high yields and very short reaction times. Mechanistically, it is interesting that trityl chloride through the in situ generation of trityl carbocation with inherent instability is efficient as a reusable homogeneous organocatalyst in neutral media. (C) 2012 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据