Synthesis of α-silylcarboxylic acids

New alpha-silylacetic acids have been prepared following a general and convenient procedure of a one-pot reaction between trimethylsilylacetate and different chlorosilanes. New derivatives of diphenyl(methyl) silylacetic acid were prepared by a direct alkylation of its dianion with benzyl-, allyl-, and alkyl halides and trimethylchlorogermane to afford new alpha-silylcarboxylic acids. (C) 2010 Elsevier Ltd. All rights reserved.