期刊
TETRAHEDRON
卷 66, 期 46, 页码 8846-8853出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2010.09.068
关键词
Cycloaddition; Click chemistry; Alkynes; Azides; Triazole-fused heterocycles
资金
- University of Bari (Italy)
A convenient synthesis of 1,2,3-triazole-fused isoindolines and dihydroisoquinolines in good to excellent yield is reported, starting from easily available terminal alkynes and (2-haloaryl)alkylazides. The method is based upon a cycloaddition reaction, via click chemistry, followed by a transition metal-catalyzed functionalization of a C-H bond. (C) 2010 Elsevier Ltd. All rights reserved.
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