Palladium-catalyzed reduction of alkynes employing HSiEt3: stereoselective synthesis of trans- and cis-alkenes

The palladium-catalyzed semi-hydrogenation of alkynes to trans- or cis-alkenes employing HSiEt3 as the reductant is developed The CuSO4 played a significant role for (he trans/cis stereoselectivity The labeling study revealed that the two olefinic hydrogen atoms came from HSiEt3 and H2O, respectively (C)) 2009 Elsevier Ltd All rights reserved