期刊
TETRAHEDRON
卷 66, 期 49, 页码 9552-9559出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2010.09.100
关键词
Regioselectivity; Cross coupling; Medicinal chemistry; Palladium; C-C coupling
资金
- Ministry of Education Sports Culture Science and Technology Japan (MEXT)
Unsymmetrical 3 5-disubstituted pyridylpiperazines were prepared from tribromopyridine in three coupling reactions Key to the success of the syntheses is the palladium-catalyzed regioselective cross-coupling reaction in the 3-position of N-(3 5-dibromo-2-pyridyl)piperazines (C) 2010 Elsevier Ltd All rights reserved
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