期刊
TETRAHEDRON
卷 66, 期 45, 页码 8615-8622出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2010.09.048
关键词
Domino reaction; Knoevenagel-hetero-Diels-Alder; O-acrylated salicylaldehyde; Aqueous medium; 3,4-Dihydrocoumarine; Thiopyran
资金
- Research Council of Sharif University of Technology
An efficient catalyst-free synthesis of novel pentacyclic thiochromone-annulated thiopyranocoumarin derivatives is achieved via domino Knoevenagel-hetero-Diels-Alder reaction of 4-hydroxy dithiocoumarin and O-acrylated salicylaldehyde derivatives in H2O as solvent. The products are formed in good yields with high regio- and stereo-selectivity. (C) 2010 Elsevier Ltd. All rights reserved.
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