期刊
TETRAHEDRON
卷 66, 期 42, 页码 8231-8237出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2010.08.057
关键词
Ugi reaction; 6-Oxo-pyrazine-2-carboxamides; Multicomponent reactions
资金
- University of Tehran
2-(2-Formyl-1H-benzimidazol-1-yl)acetic acid, as a bifunctional formyl-acid was prepared in four steps. This compound underwent one-pot reaction with primary amines, and alkyl isocyanides under Ugi conditions. A series of novel 3-oxo-1,2,3,4-tetrahydropyrazino[1,2-a]benzimidazole-1-carboxamides were obtained in moderate to excellent yields. (C) 2010 Elsevier Ltd. All rights reserved.
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