期刊
TETRAHEDRON
卷 66, 期 26, 页码 4882-4887出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2010.03.021
关键词
Oxidative carbonylation; Multicatalysis; Tylophora alkaloids; Antofine; Palladium
资金
- Novartis
- FQRNT
A rapid synthetic approach to the tylophora alkaloids antofine and 13a alpha-secoantofine is presented that makes use of a multicatalytic oxidative aminochlorocarbonylation/Friedel-Crafts reaction as the key step. This reaction, along with a one-pot, three-step telescoped process offers a three or four-pot sequence to access the title compounds in high overall yield. (C) 2010 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据