2-Aminophenyl diphenylphosphinite as a new ligand for heterogeneous palladium-catalyzed Heck-Mizoroki reactions in water in the absence of any organic co-solvent

In this article, 2-aminophenyl cliphenylphosphinite has been introduced as a new ligand for the Heck-Mizoroki reactions of aryl halides with styrene and n-butylacrylate in water in the presence of palladium acetate. This ligand is easily prepared from the reaction of chlorodiphenyl phosphine with 2-aminophenol in high yield. Pre-catalyst [Pd(OAc)(2)] in the presence of the ligand produces a black solid mass. The solid catalyst has been recycled for the reaction of bromobenzene with styrene for six runs without appreciable loss of its catalytic activity. (C) 2009 Elsevier Ltd. All rights reserved.