期刊
TETRAHEDRON
卷 65, 期 23, 页码 4562-4568出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2009.03.090
关键词
Ring strain; Norbornanes; Norbornenes; Norbornadienes; Heterobicyclic alkenes; Heterocycles
资金
- Natural Sciences and Engineering Research Council of Canada (NSERC)
- Merck Frosst Centre for Therapeutic Research
Ring strain energies (RSEs) of heterocyclic compounds are predicted compared to their analogous homocyclic compounds using the G3 method. Suitable reference compounds are devised for row 2 and row 3 heterobicyclic alkenes. Any difference in energy between the ring and the reference is due to RSE. Row 3 heterobicyclic alkene RSEs are less than those of row 2. As the electronegativity of the heteroatom increases, the RSE increases. Substitutents at the bridgehead carbons cause a decrease in RSE. [3.2.1] Heterobicyclic alkenes are significantly less strained than their [2.2.1] counterparts. Relative and absolute RSEs are reported for heterobicyclic alkenes and their derivatives. (C) 2009 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据