期刊
TETRAHEDRON
卷 65, 期 7, 页码 1444-1449出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2008.12.008
关键词
Aldol reaction; Homoproline; Michael reaction; Organocatalysis; Sulfonamides
资金
- European Social Fund
- National Resources
Sulfonamides of the non-natural amino acid homoproline and the dipeptide Pro-Phe were synthesised and evaluated for their catalytic activity in Michael and aldol reactions. Sulfonamides of homoproline outperform proline and Pro-Phe in the Michael reaction, whereas sulfonamides of Pro-Phe lead to better results in the aldol reaction. The results of the present study show that the conversion of the carboxylic group of either homoproline or dipeptide Pro-Phe to the bioisosteric acyl sulfonamide group lead to improved organocatalysts. (C) 2008 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据