4.4 Article

Benzotriazole: an efficient ligand for the copper-catalyzed N-arylation of indoles

期刊

TETRAHEDRON
卷 65, 期 40, 页码 8434-8439

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PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2009.07.050

关键词

Benzotriazole; Dihalobenzene; Cul; Indole; N-arylation

资金

  1. Department of Science and Technology (DST), Govt. of India
  2. National Institute of General Medicine [GM 070620, GM 079593]
  3. Ministry of Science and Technology, Govt. of India
  4. CSIR, India

向作者/读者索取更多资源

A general, efficient, and inexpensive method for the N-arylation of indoles using a catalytic system derived from Cul and benzotriazole is reported. Selective mono N-arylation of indoles with ortho-di-haloarenes has also been successfully achieved in good yields using this protocol. (C) 2009 Published by Elsevier Ltd.

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