An efficient, mild, and selective Ullmann-type N-arylation of indoles catalyzed by copper(I) complex

A wide range of N-arylated indoles are selectively synthesized through intermolecular C(aryl)-N bond formation from the corresponding aryl iodides and indoles through Ullmann-type coupling reactions in the presence of a catalytic amount of easily available N,N,N',N'-tetramethyl-BINAM-Cul complex under very mild reaction conditions. (C) 2009 Elsevier Ltd. All rights reserved.