期刊
TETRAHEDRON
卷 64, 期 48, 页码 10825-10830出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2008.09.021
关键词
SiO2-NHC-Cu(1); [3+2] Cycloaddition; Recyclable; Organic azides; Alkynes; Solvent-free
资金
- National Natural Science Foundation of China [20772043, 20572031]
- Key Project of Science and Technology of the Department of Education, Anhui Province, China [ZD2007005-1]
A novel SiO2-NHC-Cu(I) 3b was developed and used as a highly efficient catalyst for [3+2] cycloaddition of organic azides and terminal alkynes. In the presence of SiO2-NHC-Cu(I) 3b (1 mol %), the reactions of terminal alkynes with organic azides underwent smoothly to generate the corresponding regiospecific 1,4-disubstituted 1,2,3-triazoles in excellent yields under solvent-free reaction conditions at room temperature. Furthermore, catalyst 3b was quantitatively recovered from the reaction mixture by a simple filtration and reused for 10 cycles without loss of its activity. (C) 2008 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据