期刊
TETRAHEDRON
卷 64, 期 18, 页码 4117-4125出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2008.01.094
关键词
RA-XIX; RA-XX; RA-XXI; RA-XXII; Rubia cordifolia; bouvardin; cytotoxicity
Novel bicyclic hexapeptides, RA-XIX, -XX, -XXI, and -XXII, were isolated from the roots of Rubia cordifolia L. The structures of RA-XIX and RA-XX were established by semisynthesis from a cycloisodityrosine, derived from previously reported RA-VII, and those of RA-XXI and RA-XXII by chemical correlation with RA-XX and previously reported RA-VIII, respectively. The IC(50) values of these new peptides against P-388 leukemia cells were 0.013-0.63 mu g/mL. (c) 2008 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据