期刊
TETRAHEDRON
卷 64, 期 1, 页码 240-247出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2007.10.081
关键词
oxygen donor ligands; nitrogen donor; palladium complex; catalysis; suzuki cross-coupling; Mizoroki-Heck reactions
A bulky, inexpensive and simple bidentate ligand 1,4-bis(2-hydroxy-3,5-di-tert-butylbenzyl)piperazine (1) has been synthesized and characterized. The palladium catalyst was formed by combination of 1 with [Cl2Pd(COD)] in a ratio of 1:1, tested in the Suzuki-Miyaura and Mizoroki-Heck cross-coupling reactions. Coupling of a variety of aryl bromides with phenylboronic acid using methanol as solvent at room temperature, or at 60 degrees C, gave aenerally high yields of coupled products. Coupling of aryl chlorides with organoboron reagent at 110 degrees C in DMF afforded good yields of biaryls under aerobic conditions. This non-phosphorus, air and moisture stable catalyst also displays good activity for Mizoroki-Heck coupling reaction in methanol at 60 degrees C with various aryl chlorides and bromides. (c) 2007 Elsevier Ltd. All fights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据