期刊
TECHNOLOGY IN CANCER RESEARCH & TREATMENT
卷 11, 期 5, 页码 475-481出版社
SAGE PUBLICATIONS INC
DOI: 10.7785/tcrt.2012.500259
关键词
Drug delivery systems; Liposomal nanoparticles; Cancer therapy; Genetic drugs; Targeting
类别
资金
- Key New Drug Discovery Project of 11th Five-Years Plan [2009ZX09103-680]
- Ministry of Science and Technology of the People's Republic of China
- Natural Science Foundation of Zhejiang Province [Y2111250]
- Key Science and Technology Project of Huzhou City [2011GG14]
Drug delivery systems (DDS) are designed to improve the pharmacological and therapeutic effect. In the past few decades, there are some problems that impeded applications of particulate DDS have been resolved, with several DDS formulations of anticancer now approved for clinical use. Liposomal nanoparticles (LNs) encapsulating therapeutic agents have been recognized as one of the most advanced classes of DDS. Liposomal nanoparticles (LNs) could encapsulate both conventional anticancer drugs and the new genetic drugs with several properties such as high drug-to-lipid ratio, excellent retention of drug and a long circulation lifetime. These excellent properties of LNs have the potentials to offer new treatments in area of cancer therapy. Here, we will discuss recent advances in this field involving conventional anticancer drugs as well as the new genetic drugs.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据