A ratiometric fluorescent probe for hydrogen sulfide imaging in living cells

We herein report a turn-on fluorescent probe based on excited state intramolecular proton transfer (ESIPT) mechanism and self-immolative linker for hydrogen sulfide detection. The new probe exhibits high sensitivity and selectivity over other biologically relevant anions. Moreover, we show the utility of the probe for the detection of hydrogen sulfide in living cells as well. (C) 2014 Elsevier B.V. All rights reserved.