期刊
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
卷 12, 期 6, 页码 6858-6878出版社
MDPI AG
DOI: 10.3390/ijerph120606858
关键词
energy available; energy consumption; energy budget; Oligochaeta; nanomaterials
资金
- FEDER through COMPETE Programa Operacional Factores de Competitividade
- National funding through FCT-Fundacao para a Ciencia e Tecnologia [NANOkA FCOMP-01-0124-FEDER-008944 (Ref. FCT PTDC/BIA-BEC/103716/2008)]
- National funding through FCT PhD grant [SFRH/BD/63261/2009]
- EU [263215, 604305]
- Fundação para a Ciência e a Tecnologia [SFRH/BD/63261/2009] Funding Source: FCT
The effects of several copper (Cu) and silver (Ag) nanomaterials were assessed using the cellular energy allocation (CEA), a methodology used to evaluate the energetic status and which relates with organisms' overall condition and response to toxic stress. Enchytraeus crypticus (Oligochatea), was exposed to the reproduction effect concentrations EC20/(50) of several Cu and Ag materials (CuNO3, Cu-Field, Cu-Nwires and Cu-NPs; AgNO3, Ag NM300K, Ag-NPs Non-coated and Ag-NPs PVP-coated) for 7 days (0-3-7d). The parameters measured were the total energy reserves available (protein, carbohydrate and lipid budgets) and the energy consumption (Ec) integrated to obtain the CEA. Results showed that these parameters allowed a clear discrimination between Cu and Ag, but less clearly within each of the various materials. For Cu there was an increase in Ec and protein budget, while for Ag a decrease was observed. The results corroborate known mechanisms, e.g., with Cu causing an increase in metabolic rate whereas Ag induces mitochondrial damage. The various Cu forms seem to activate different mechanisms with size and shape (e.g., Cu-NPs versus Cu-Nwires), causing clearly different effects. For Ag, results are in line with a slower oxidation rate of Ag-NMs in comparison with Ag-salt and hence delayed effects.
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