期刊
TALANTA
卷 105, 期 -, 页码 333-339出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.talanta.2012.10.050
关键词
Inkjet printing; Conducting polymers; Bioelectronics; Biosensors; Exocytosis
资金
- WCU (World Class University) program through the National Research Foundation of Korea
- Ministry of Education, Science and Technology [R31-10013]
Polyaniline (PANi) patterns on flexible substrate are fabricated for biomolecule detection from live cells. PANi patterns are prepared by inkjet printing on polyethylene terephthalate film. Subsequently, arginine-glycine-aspartate (RGD) peptide is immobilized on the PANi pattern to selectively adhere cells. Rat pheochromocytoma PC12 cells are cultured on the RGD-immobilized PANi pattern, and patterned with high selectivity and growth. Additionally, the cells show focal adhesion on the RGD-immobilized PANi pattern, which are confirmed with vinculin staining and scanning electron microscopic images. To monitor dynamic biomolecular release from PC12 cells, RGD-immobilized PANi pattern is used for a real-time electrical signal detector. RGD-immobilized PANi patterning and sensing system represents outstanding ability to translate and amplify exocytosis molecules into a detectable signal as a transducer. (C) 2012 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据