A piezoelectric immunosensor for chloramphenicol detection in food

A piezoelectric immunosensor on the basis of electrogenerated polymer for detecting trace quantities of chloramphenicol, a drug which is used in veterinary for treatment and prevention of infectious diseases, was developed. The detection was conducted in a competitive format with the use of hapten-protein conjugate and monoclonal antibodies. The limit of detection is 0.2 ng ml(-1), the calibration curve is linear in the range of concentrations 0.5-100.0 ng ml(-1). Chloramphenicol was detected in food (meat, milk, egg, honey). (C) 2011 Elsevier B.V. All rights reserved.