期刊
TALANTA
卷 82, 期 3, 页码 1033-1037出版社
ELSEVIER
DOI: 10.1016/j.talanta.2010.06.015
关键词
Artemisinin; Quantity; UV-visible spectroscopy
A sensitive and rapid spectrophotometric method for determination of artemisinin concentration is described. The method is based on the measurement of a reaction product of the drug in strong alkali solution. The interaction produces a homogenous electronic transition band from 250 to 330 nm with maximum transition at around 291 nm. The absorption curve shows Gaussian distribution with identical half bandwidth, thus providing information for formation of a possible mono-type reaction product. The 291 nm absorption intensity increases with increasing concentration of artemisinin and obeys Beer's law in the range of 0.44-172 nmol (ml(-1)). The optimum reaction conditions and other analytical parameters were evaluated including its recovery from human plasma and erythrocyte samples. (C) 2010 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据