期刊
SYNTHETIC COMMUNICATIONS
卷 43, 期 11, 页码 1549-1556出版社
TAYLOR & FRANCIS INC
DOI: 10.1080/00397911.2011.647222
关键词
Antifungal activity; chromones; flavonoids; heterocycles
资金
- Egyptian Ministry of Higher Education and State for Scientific Research (MHESR) under the ParOwn programe
A one-pot method for the synthesis of chromone derivatives from the reaction of 2-hydroxyacetophenones with aliphatic or aromatic acid chlorides is reported. Esterification and Baker-Venkataraman rearrangement were promoted by t-BuOK, which was followed directly by acid-catalyzed cyclization in one pot. Some of 2-cyclohexyl- and 2-cyclohexylmethyl-substituted chromones displayed activity against plant pathogenic fungal strains. Supplemental materials are available for this article. Go to the publisher's online edition of Synthetic Communications (R) to view the free supplemental file.
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