期刊
SYNTHETIC COMMUNICATIONS
卷 41, 期 20, 页码 3026-3031出版社
TAYLOR & FRANCIS INC
DOI: 10.1080/00397911.2010.516461
关键词
5-Alkylfuran-2(5H)-ones; condensation; elimination; lactonization; neutral alumina
A convenient synthesis of 5-alkylfuran-2(5H)-ones are described starting from 3-nitropropanoate and aldehydes, promoted by neutral alumina, in 35-60% overall yields, via a condensation-lactonization-elimination pathway.
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