期刊
SYNTHETIC COMMUNICATIONS
卷 39, 期 12, 页码 2205-2220出版社
TAYLOR & FRANCIS INC
DOI: 10.1080/00397910802654666
关键词
Biginelli reaction; 3; 4-Dihydropyrimidin-2(1H)-one; one-pot multicomponent synthesis; trimethylsilyl chloride
资金
- Natural Science Foundation of Zhejiang Province, China [Y407240]
3,4-Dihydropyrimidin-2(1H)-one and their derivatives were synthesized in good yields (90-99%) by a one-pot, three-component Biginelli cyclocondensation of dimedone, aldehydes, and urea in the presence of trimethylsilyl chloride (TMSCl) in dimethylformamide (DMF).
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