4.3 Article

One-Pot Synthesis of 3,4-Dihydropyrimidine-2-(1H)-ones Using CsF-Celite as Catalyst

期刊

SYNTHETIC COMMUNICATIONS
卷 39, 期 5, 页码 880-886

出版社

TAYLOR & FRANCIS INC
DOI: 10.1080/00397910802439175

关键词

Celite; cesium fluoride; dihydropyrimidinones; green chemistry; multicomponent reaction

资金

  1. Commission on Higher Education (CHE-RG)
  2. Center for Innovation in Chemistry
  3. Postgraduate Education Program in Chemistry (PERCH-CIC)

向作者/读者索取更多资源

A facile, efficient, and environmentally benign procedure for the synthesis of 3,4-dihydropyrimidin-2-(1H)-ones via the cyclocondensation reaction of aromatic aldehyde, ethyl acetoaceate, and urea catalyzed by CsF-Celite was developed. This environmentally friendly method is superior to previous methods with respect to reaction time, yield, and workup.

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