4.3 Article

Phosphomolybdic acid/SiO2 as heterogeneous solid acid catalyst for the rapid synthesis of N-substituted pyrroles

期刊

SYNTHETIC COMMUNICATIONS
卷 38, 期 20, 页码 3456-3464

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TAYLOR & FRANCIS INC
DOI: 10.1080/00397910802157843

关键词

heteropoly acid; 4-hydroxy proline; isatins; pyrroles

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Isatins react efficiently with 4-hydroxyproline in the presence of 10mol% of PMA/SiO2 in acetonitrile/water (4:1) under reflux conditions to furnish N-substituted pyrroles in excellent yields. Similarly, 11H-indeno[1,2-b]quinoxalin-11-ones also participated in this reaction.

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