期刊
SYNTHETIC COMMUNICATIONS
卷 38, 期 19, 页码 3260-3269出版社
TAYLOR & FRANCIS INC
DOI: 10.1080/00397910802116583
关键词
coenzymes; diadenosine; morpholidate; pyrophosphate
资金
- Italian Association for Cancer Research (AIRC)
- Italian Ministry for Education
- University and Scientific Research [MIUR-PRIN 2003, MIUR FIRB RBNE01ERXR, MIUR FIRB RBLA039LSF]
- Fondazione Cassa di Risparmio di Genova e Imperia
Pyrophosphate-linked coenzymes play essential roles in several biochemical systems. Symmetrical diadenosine-5'-pyrophosphate (Ap2A) has been synthesized from adenosine-5'-phosphate in virtually quantitative yield. The simple procedure is carried out in anhydrous pyridine using adenosine phosphoromorpholidate and adenosine monophosphate bis-(tri-n-butylammonium salt) as coupling reagents.
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