Na 2 CO 3 -Catalyzed N -Acylation of Indoles with Alkenyl Carboxylates

The N -acylation of indoles has been accomplished via inorganic base catalysis. It provided an efficient and simple catalysis system for the preparation of N -acylindoles with alkenyl carboxylates as acylating agents. A broad variety of indoles undergo the smooth N -acylation using Na (2) CO (3) as catalyst in MeCN at 120 degrees C to give the corresponding N -acylindoles in good to excellent yields.