期刊
SYNTHESIS-STUTTGART
卷 46, 期 11, 页码 1511-1517出版社
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0033-1340978
关键词
biotin; vitamins; antibiotics; amino acid; benzotriazole method; microwave-assisted reaction
资金
- University of Florida
- Kenan Foundation
- King Abdulaziz University [D-006/431]
- KAU
Benzotriazole-activated biotin was utilized as a versatile building block for the efficient and convenient synthesis of novel biotin conjugates with quinolone antibiotics via amino acid linkers under microwave irradiation. The products are obtained in yields of 70-91% with retention of chirality.
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