4.5 Article

Synthesis of Quinolines via Friedlander Reaction in Water and under Catalyst-Free Conditions

期刊

SYNTHESIS-STUTTGART
卷 44, 期 3, 页码 389-392

出版社

GEORG THIEME VERLAG KG
DOI: 10.1055/s-0031-1289657

关键词

catalyst-free; water; Friedlander reaction; ketones; quinolines

资金

  1. National Nature Science Foundation of China [20672035]
  2. Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences

向作者/读者索取更多资源

A straightforward and efficient method for the synthesis of quinolines via Friedlander reaction of 2-aminobenzaldehyde with various ketones or malononitrile in water without using any catalyst at 70 degrees C is reported.

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