期刊
SYNTHESIS-STUTTGART
卷 -, 期 12, 页码 1946-1953出版社
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0030-1260032
关键词
alpha-chloroaldehydes; aldol reaction; stereoselective synthesis; heterocycles; natural products
资金
- NSERC Canada
- Michael Smith Foundation for Health Research
- NSERC CGSD
- NSERC PGSD
The lithium aldol reaction of alpha-chloroaldehydes provides 1,2-anti-configured beta-ketochlorohydrins. The scope of this reaction is demonstrated as well as its application to the synthesis of the C4-C15 segment of haterumalide NA.
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