期刊
SYNTHESIS-STUTTGART
卷 -, 期 15, 页码 2631-2635出版社
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0029-1218827
关键词
trichloroisocyanuric acid; nitriles; alcohols; amines; aldehydes; alkyl halides
A new and efficient procedure for the one-pot conversion of various alcohols, aldehydes and primary amines into the corresponding nitriles in excellent yields was easily achieved by trichloroisocyanuric acid (TCCA) as an oxidant and reagent in aqueous ammonia. Also, various benzylic halides were smoothly and directly converted into the corresponding aromatic nitriles in high yields under the same conditions.
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