期刊
SYNTHESIS-STUTTGART
卷 -, 期 23, 页码 4043-4050出版社
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0030-1258261
关键词
aqueous medium; domino Knoevenagel-hetero-Diels-Alder reaction; stereoselective; regioselective; 4-hydroxydithiocoumarin
资金
- CSIR (New Delhi)
- DST (New Delhi)
Benzopyran-annulated thiopyrano[2,3-b] thiochromen-5(4H)-ones have been synthesized by the domino Knoevenagelhetero-Diels-Alder (DKHDA) reaction of 4-hydroxydithiocoumarin with O-allylated salicylaldehyde and O-propargylated salicylaldehyde in aqueous medium. The reaction requires only a single step operation and is highly regio- and stereoselective providing potentially bioactive polycyclic heterocycles in high yields.
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