4.4 Article

A Practical Method for Metal-Free Radical Trifluoromethylation of Styrenes with NaSO2CF3

期刊

SYNLETT
卷 25, 期 9, 页码 1307-1311

出版社

GEORG THIEME VERLAG KG
DOI: 10.1055/s-0033-1341057

关键词

metal-free; trifluoromethylation; ketones; alcohols; Langlois reagent; styrenes

资金

  1. NSF of Jiangxi Provincial Education Department [GJJ12570, KJLD13081]
  2. China Scholarship Council

向作者/读者索取更多资源

A mild and practical protocol for the metal-free trifluoromethylation of styrenes using NaSO2CF3 (Langlois reagent) and TBHP was developed. The approach provides efficient access to -trifluoromethylated ketones and alcohols in moderate to good yields.

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