An Efficient Synthesis of 2,4,6-Triarylpyridines via Solvent-Free Reaction between Acetophenoneoximes and Aldehydes

An efficient synthesis of 2,4,6-triarylpyridines is described. Heating a mixture of an acetophenoneoxime and an aldehyde under solvent-free conditions afforded Krohnke pyridines in excellent yields. In this method acetophenoneoximes are directly used for the preparation of Krohnke pyridines under metal-free conditions.