4.4 Article

p-Toluenesulfonic Acid Catalyzed One-Pot Synthesis of 4H-Pyrido[1,2-a]pyrimidin-4-one Derivatives

期刊

SYNLETT
卷 25, 期 10, 页码 1478-1481

出版社

GEORG THIEME VERLAG KG
DOI: 10.1055/s-0033-1339012

关键词

metal-free; 4H-pyrido[1,2-a]pyrimidin-4-ones; PTSA; 2-aminopyridine; multicomponent reactions

资金

  1. Foundation for Natural Science Foundation of Guangdong Province [S2013040012962]
  2. Distinguished Young Talents in Higher Education of Guangdong [2012LYM_0086]
  3. National Natural Science Foundation of China [21302023]

向作者/读者索取更多资源

A novel one-pot protocol has been developed for the construction of alkenylated 4H-pyrido[1,2-a]pyrimidin-4-one derivatives from 2-aminopyridine in the presence of PTSA. The present approach opens a new way for the formation of C-C and C-N bonds under mild conditions.

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