4.4 Article

A Microwave-Assisted Three-Component Synthesis of Arylaminomethyl Acetylenes: A Facile Access to Terminal Alkynes

期刊

SYNLETT
卷 25, 期 3, 页码 407-410

出版社

GEORG THIEME VERLAG KG
DOI: 10.1055/s-0033-1340331

关键词

microwave-assisted; three-component; ammonia; propargyl halide; terminal alkynes

资金

  1. National Natural Science Foundation of China [21262020, 51363012]
  2. Science and Technology Planning Project of Yunnan Province [KKSY201207047]

向作者/读者索取更多资源

A simple, rapid, one-pot synthesis of arylaminomethyl acetylenes is achieved under microwave-assisted conditions (power=5 W) using aromatic boronic acids, aqueous ammonia, propargyl halides, copper(I) oxide and water as the solvent. The reactions are complete within ten minutes affording good to excellent yields of the products.

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